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The class of drugs called ACE inhibitors is commonly used for the treatment of elevated blood pressureThis class includes drugs such as ramiprilbrand nameAltacecaptoprilCapotenenalaprilVasotecfosinoprilMonoprillisinoprilPrinivilZestriland quinaprilAccuprilWe asked how much this class of drugs lowers blood pressure and whether there is a difference between individual drugs within the classThe available scientific literature was searched to find all the trials that had assessed this question.
Neutropenia/AgranulocytosisAgranulocytosis and bone marrow depression have been caused by angiotensin converting enzyme inhibitorsSeveral cases of agranulocytosis and neutropenia have been reported in which a causal relationship to lisinopril cannot be excludedCurrent experience with the drug shows the incidence to be rarePeriodic monitoring of white blood cell counts should be consideredespecially in patients with collagen vascular disease and renal disease.
Do not use Prinivil if you are pregnantIf you become pregnantstop taking this medicine and tell your doctor right awayPrinivil can cause injury or death to the unborn baby if you take the medicine during your second or third trimesterUse effective birth control while taking Prinivil.
All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volumeOther causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressurepatients should be advised to consult with their physician.
Avoid becoming overheated or dehydrated during exercisein hot weatheror by not drinking enough fluidsPrinivil can decrease sweating and you may be more prone to heat stroke.
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